Anti-kanaka IL6, Mouse Monoclonal
Nā kikoʻī huahana
ʻIke Nui
ʻO Interleukin-6 (IL-6) he cytokine α-helical multifunctional e hoʻoponopono ana i ka ulu ʻana o nā cell a me ka hoʻokaʻawale ʻana o nā ʻiʻo like ʻole, i ʻike nui ʻia no kāna kuleana i ka pane ʻana o ka immune a me nā hopena o ka manawa.Ua hūnā ʻia ka protein IL-6 e nā ʻano cell like ʻole me nā cell T a me nā macrophages ma ke ʻano he phosphorylated a variably glycosylated mole.Hoʻohana ia i nā hana ma o kāna mea hoʻokipa heterodimeric i haku ʻia me IL-6R i nele i ka tyrosine/kinase domain a hoʻopaʻa iā IL-6 me ka haʻahaʻa haʻahaʻa, a me ka glycoprotein 130 (gp130) i hōʻike ʻia i nā wahi āpau e hoʻopaʻa i ka IL-6.IL-6R paʻakikī me ka pilina kiʻekiʻe a no laila e hoʻololi i nā hōʻailona.Hoʻokomo pū ʻia ʻo IL-6 i ka hematopoiesis, ka iwi metabolism, a me ka piʻi ʻana o ka maʻi maʻi, a ua wehewehe ʻia he kuleana koʻikoʻi i ke alakaʻi ʻana i ka hoʻololi ʻana mai ka innate i ka loaʻa ʻana o ka palekana.
Waiwai
| Manaʻo Pair | CLIA (Hopu-Hopu): 1B1-4 ~ 2E4-1 2E4-1 ~ 1B1-4 |
| Maemae | >95%, hoʻoholo ʻia e SDS-PAGE |
| ʻO ka hoʻopololei ʻana | PBS, pH7.4. |
| Waihona | E mālama iā ia ma lalo o nā kūlana sterile ma -20 ℃ a -80 ℃ ma ka loaʻa ʻana. Manaʻo e hoʻokaʻawale i ka protein i nā mea liʻiliʻi no ka mālama maikaʻi ʻana. |
Hoʻohālikelike hoʻokūkū
Ka hoʻopili ʻana-<120pg>
Ka nānā 'ana i ka pilina -1.5-5000pg/mL
ʻIke Kauoha
| inoa mea kūʻai | Cat.ʻAʻole | Klone ID |
| IL6 | AB0001-1 | 1B1-4 |
| AB0001-2 | 2E4-1 | |
| AB0001-3 | 2C3-1 |
'Ōlelo Aʻo: Hiki i ka Bioantibody ke hoʻololi i ka nui o kāu pono.
Kuhikuhi
1.Zhong Z, Darnell ZW, Jr. Stat3: he lālā o ka ʻohana STAT i hoʻāla ʻia e ka tyrosine phosphorylation ma ka pane ʻana i ka mea ulu epidermal a me interleukin-6[J].ʻEpekema, 1994.
2.J, Bauer, F, et al.ʻO Interleukin-6 i ka lāʻau lapaʻau [J].Nā Annals of Hematology, 1991.
