Anti-kanaka MPO Antibody, Mouse Monoclonal

ʻIke Nui
ʻO MPO (myeloperoxidase) he enzyme peroxidase i hūnā ʻia e nā leukocytes i hoʻāla ʻia e pāʻani ana i kahi kuleana pathogenic i ka maʻi cardiovascular, ʻoi loa ma ka hoʻomaka ʻana i ka endothelial dysfunction.ʻO ka Myeloperoxidase (MPO) he enzyme koʻikoʻi, ʻo ia kekahi o nā ʻāpana o ka ʻōnaehana antibacterial i nā neutrophils a me nā monocytes.Hoʻokomo ʻo MPO i ka pane ʻeha ma nā wahi he nui o ke kino, me ka mammary glands.Ua hoʻohana mua ʻia ʻo Myeloperoxidase (MPO), kahi enzyme leukocyte polymorphonuclear kikoʻī, e helu i ka helu o nā neutrophils i loko o ke kiko.Ua ʻike ʻia ka hana ʻana o MPO e pili ana i ka helu o nā cell neutrophil.He kuleana koʻikoʻi ka ʻōnaehana MPO i ka hoʻomalu ʻana i nā maʻi a me ka holoi ʻana i nā cell malignant.Eia nō naʻe, hiki i ka hoʻololi ʻana i ka ʻōnaehana MPO ke alakaʻi i ka pōʻino DNA a me ka carcinogenesis.ʻO nā polymorphisms i loko o ka MPO gene ua pili pū me ka hoʻonui ʻana i ka hōʻike o MPO a me kahi kiʻekiʻe kiʻekiʻe no ka ulu ʻana o ka maʻi kanesa.ʻO Myeloperoxidase (MPO) kekahi o nā antigens pahuhopu nui o antineutrophil cytoplasmic autoantibodies (ANCA) i loaʻa i nā maʻi me ka vasculitis moku liʻiliʻi a me ka glomerulonephritis necrotizing Pauci-immune.ʻO ka Myeloperoxidase-anti-neutrophil cytoplasmic antibody (MPO-ANCA) he autoantibody i loaʻa pinepine i nā maʻi me nā vasculitides.