Anti-kanaka GH Antibody, Mouse Monoclonal

ʻIke Nui
ʻO ka hormone ulu (GH) a i ʻole somatotropin, i ʻike ʻia ʻo ka hormone ulu kanaka (hGH a i ʻole HGH), he hormone peptide e hoʻoulu ai i ka ulu ʻana, ka hana hou ʻana o ka cell, a me ka hoʻōla hou ʻana o nā cell i loko o ke kanaka a me nā holoholona ʻē aʻe.No laila, he mea nui ia i ka ulu ʻana o ke kanaka.Hoʻoulu pū ʻo GH i ka hana ʻana o IGF-1 a hoʻonui i ka ʻike o ka glucose a me nā ʻakika momona manuahi.He ʻano mitogen ia i kikoʻī wale i nā mea loaʻa ma kekahi ʻano o nā cell.ʻO GH he 191-amino acid, hoʻokahi-chain polypeptide i hoʻohui ʻia, mālama ʻia a hūnā ʻia e nā cell somatotropic i loko o nā ʻēheu ʻaoʻao o ka pituitary gland anterior.

Hoʻohana ʻia nā hoʻokolohua GH e ʻike i nā maʻi GH, me:
★ GH hemahema.I nā keiki, pono ka GH no ka ulu maʻamau a me ka ulu ʻana.Hiki i ka hemahema o ka GH ke ulu mālie a ʻoi aku ka pōkole ma mua o nā keiki o ka makahiki like.I nā mākua, hiki i ka hemahema GH ke alakaʻi i ka iwi iwi haʻahaʻa a hoʻemi i ka nui o ka ʻiʻo.
★ Pilikia.He maʻi maʻi ʻōpiopio kēia e hoʻohua nui ai ke kino i ka GH.He kiʻekiʻe loa nā keiki me ka gigantism no ko lākou mau makahiki a nui nā lima a me nā wāwae.
★ Acromegaly.ʻO kēia maʻi, e pili ana i nā mākua, ke kumu o ke kino e hoʻohua nui i ka hormone ulu.ʻOi aku ka mānoanoa o ka poʻe me ka acromegaly ma mua o nā iwi maʻamau a hoʻonui ʻia nā lima, nā wāwae, a me nā hiʻohiʻona maka.