ʻIke Nui
ʻO Vascular endothelial growth factor (VEGF), ʻike ʻia hoʻi ʻo vascular permeability factor (VPF) a me VEGF-A, he mea hoʻolaha ikaika o ka angiogenesis a me ka vasculogenesis i ka pēpē a me ke kanaka makua.He lālā ia o ka ʻohana platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) a ke noho mau nei ma ke ʻano he homodimer pili disulfide.ʻO ka protein VEGF-A he glycosylated mitogen e hana pono ana i nā cell endothelial a loaʻa nā hopena like ʻole, me ka mediating hoʻonui vascular permeability, hoʻoulu i ka angiogenesis, vasculogenesis a me ka ulu ʻana o ka endothelial cell, hoʻoikaika i ka neʻe ʻana o ka cell, inhibiting apoptosis a me ka ulu ʻana o ka tumor.ʻO ka protein VEGF-A kekahi vasodilator e hoʻonui ai i ka microvascular permeability, no laila ua kapa mua ʻia ʻo ia he vascular permeability factor.
Manaʻo Pair | CLIA (Hopu-Hopu): 12A4-7 ~ 5F6-2 2B4-6 ~ 5F6-2 |
Maemae | >95%, hoʻoholo ʻia e SDS-PAGE |
ʻO ka hoʻopololei ʻana | PBS, pH7.4. |
Waihona | E mālama iā ia ma lalo o nā kūlana sterile ma -20 ℃ a -80 ℃ ma ka loaʻa ʻana. Manaʻo e hoʻokaʻawale i ka protein i nā mea liʻiliʻi no ka mālama maikaʻi ʻana. |
inoa mea kūʻai | Cat.ʻAʻole | Klone ID |
VEGFA | AB0042-1 | 2B4-6 |
AB0042-2 | 12A4-7 | |
AB0042-3 | 5F6-2 |
'Ōlelo Aʻo: Hiki i ka Bioantibody ke hoʻololi i ka nui o kāu pono.
1.Tammela T, Enholm B, Alitalo K, et al.ʻO ka biology o nā kumu ulu endothelial vascular [J].Noiʻi maʻi cardiovascular, 2005, 65 (3): 550.
2.Wolfgang, Lieb, Radwan, et al.Vascular endothelial growth factor, its soluble receptor, and hepatocyte growth factor: clinical and genetic correlates and association with vascular function.[J].Puka Puʻuwai ʻEulopa, 2009.