Anti-kanaka RBP4 Antibody, Mouse Monoclonal
Nā kikoʻī huahana
ʻIke Nui
ʻO Retinol-binding protein 4 (RBP4) ka mea lawe kikoʻī no ka retinol (ʻike pū ʻia ʻo ka vitamina A), a nona ke kuleana no ka hoʻololi ʻana o ka retinol paʻa ʻole a hiki ʻole ke hoʻoheheʻe ʻia i loko o ka wai i loko o ka paʻa paʻa a hiki ke hoʻoheheʻe ʻia i loko o ka plasma ma o kā lākou pilina paʻa.Ma ke ʻano he lālā o ka lipocalin superfamily, ua hūnā ʻia ʻo RBP4 i loko o kahi hale β-barrel me kahi lua i wehewehe maikaʻi ʻia mai ke akepaʻa, a ʻo ia hoʻi e hoʻopuka i ka retinol mai nā hale kūʻai o ke ake i nā ʻiʻo peripheral.I loko o ka plasma, pili ka RBP4-retinol complex me transthyretin (TTR), a he mea koʻikoʻi kēia paʻa no ka pale ʻana i ka RBP4 excretion ma o ka glomeruli kidney.ʻO RBP4 i hōʻike ʻia mai kahi kumu ectopic e hāʻawi maikaʻi i ka retinol i nā maka, a ʻo kona hemahema e pili nui i ka ʻike pō.I kēia mau lā, ʻike ʻia ʻo RBP4 ma ke ʻano he adipokine, i hōʻike ʻia i loko o ke kiko adipose a hoʻopili ʻia me ka momona, ka insulin resistance (IR) a me ka type 2 diabetes (T2DM).
Waiwai
| Manaʻo Pair | CLIA (Hopu-Hopu): 9D11-8 ~ 3D4-1 3C8-1 ~ 3D4-1 |
| Maemae | >95% e like me ka mea i hoʻoholo ʻia e SDS-PAGE. |
| ʻO ka hoʻopololei ʻana | PBS, pH7.4. |
| Waihona | E mālama iā ia ma lalo o nā kūlana sterile ma -20 ℃ a -80 ℃ ma ka loaʻa ʻana. Manaʻo e hoʻokaʻawale i ka protein i nā mea liʻiliʻi no ka mālama maikaʻi ʻana. |
Hoʻohālikelike hoʻokūkū
ʻIke Kauoha
| inoa mea kūʻai | Cat.ʻAʻole | Klone ID |
| RBP4 | AB0032-1 | 9D11-8 |
| AB0032-2 | 3C8-1 | |
| AB0032-3 | 3D4-1 | |
| AB0032-4 | 1C6-1 |
'Ōlelo Aʻo: Hiki i ka Bioantibody ke hoʻololi i ka nui o kāu pono.
Kuhikuhi
1.Aiwei YB, Vijayalakshmi V, Bodles AM, et al.ʻO ka Retinol binding protein 4 hōʻike i loko o ke kanaka: ka pilina me ke kū'ēʻana o ka insulin, ka mumū, a me ka paneʻana i ka pioglitazone.[J].J Clin Endocrinol Metab(7):2590-2597.
2.Haider DG, Karin S, Gerhard P, et al.Hoʻemi ʻia ka serum retinol-binding protein 4 ma hope o ka lilo ʻana o ke kaumaha ma nā mea momona momona.[J].Nūpepa o Clinical Endocrinology & Metabolism(3):1168-71.
