ʻIke Nui
ʻO IGFBP1, i kapa ʻia ʻo IGFBP-1 a me ka insulin-like growth factor-binding protein 1, he lālā ia o ka ʻohana protein-like growth factor-binding protein.ʻO nā protein paʻa IGF (IGFBPs) he mau protein o 24 a 45 kDa.Hoʻokaʻawale nā IGFBP ʻeono i ka 50% homology a loaʻa iā lākou nā pilina pili no IGF-I a me IGF-II ma ke ʻano like o ka nui e like me nā ligands no ka IGF-IR.ʻO nā protein paʻa IGF e hoʻolōʻihi i ka hapalua o ke ola o nā IGF a ua hōʻike ʻia i ke kāohi a i ʻole ka hoʻoulu ʻana i nā hopena hoʻoulu ulu o nā IGF ma ka moʻomeheu cell.Hoʻololi lākou i ka launa pū ʻana o nā IGF me kā lākou mau mea hoʻokipa ʻili.Loaʻa i ka IGFBP1 kahi kikowaena IGFBP a me kahi kikowaena thyroglobulin type-I.Hoʻopaʻa ia i nā mea ulu like like me ka insulin (IGFs) I a me II a holo i loko o ka plasma.ʻO ka hoʻopaʻa ʻana o kēia pūmua e hoʻolōʻihi i ka hapalua o ke ola o nā IGF a hoʻololi i kā lākou launa pū me nā mea hoʻokipa ʻili.
Manaʻo Pair | CLIA (Hopu-Hopu): 4H6-2 ~ 4C2-3 4H6-2 ~ 2H11-1 |
Maemae | >95% e like me ka mea i hoʻoholo ʻia e SDS-PAGE. |
ʻO ka hoʻopololei ʻana | 20 mM PB, 150 mM NaCl, 0.1% Proclin 300, pH7.4 |
Waihona | E mālama iā ia ma lalo o nā kūlana sterile ma -20 ℃ a -80 ℃ ma ka loaʻa ʻana. Manaʻo e hoʻokaʻawale i ka protein i nā mea liʻiliʻi no ka mālama maikaʻi ʻana. |
Bioantibody | Ka ma'i ma'i ma'i | Huina | |
maikaʻi | ʻinoʻino | ||
maikaʻi | 35 | 0 | 35 |
ʻinoʻino | 1 | 87 | 88 |
Huina | 36 | 87 | 123 |
kikoo | 100% | ||
ʻO ka ʻike | 97% |
inoa mea kūʻai | Cat.ʻAʻole | Klone ID |
IGFBP-1 | AB0028-1 | 4H6-2 |
AB0028-2 | 4C2-3 | |
AB0028-3 | 2H11-1 | |
AB0028-4 | 3G12-11 |
'Ōlelo Aʻo: Hiki i ka Bioantibody ke hoʻololi i ka nui o kāu pono.
1.Rutanen EM .ʻO ka mea ulu e like me ka insulin e hoʻopaʻa ana i ka protein 1: US 1996.
2. Harman, S, Mitchell, et al.Nā Kūlana Serum o ka Insulin-Like Growth Factor I (IGF-I), IGF-II, IGF-Binding Protein-3, a me Prostate-Specific Antigen ma ke ʻano he Predictors of Clinical Prostate Cancer [J].Nūpepa o Clinical Endocrinology & Metabolism, 2000.