ʻIke Nui
ʻO S100B kahi protein paʻa calcium, i hūnā ʻia mai nā astrocytes.He protein cytosolic dimeric liʻiliʻi (21 kDa) nona nā kaulahao ββ a i ʻole αβ.Hoʻokomo ʻia ʻo S100B i nā ʻano hana hoʻoponopono intracellular a extracellular.
I loko o nā makahiki he ʻumi i hala iho nei, ua puka mai ʻo S100B ma ke ʻano he moho peripheral biomarker o ka pōʻino koko-lolo (BBB) a me ka hōʻeha CNS.Hōʻike pololei nā pae kiʻekiʻe S100B i ka hiki ʻana o nā kūlana neuropathological me ka ʻeha poʻo traumatic a me nā maʻi neurodegenerative.ʻO nā pae S100B maʻamau e haʻalele i ka pathology CNS nui.Ua hōʻike pū ʻia ʻo Serum S100B ma ke ʻano he hōʻailona pono no ka ʻike mua ʻana i nā metastases o ka melanoma a me nā pilikia cerebral mai ka hōʻeha poʻo, ka ʻoki ʻana i ka naʻau, a me ka hahau ʻana.
Manaʻo Pair | CLIA (Hopu-Hopu): 5H2-3 ~ 22G7-5 22G7-5 ~ 5H2-3 |
Maemae | >95% e like me ka mea i hoʻoholo ʻia e SDS-PAGE. |
ʻO ka hoʻopololei ʻana | 20 mM PB, 150 mM NaCl, 0.1% Proclin 300, pH7.4 |
Waihona | E mālama iā ia ma lalo o nā kūlana sterile ma -20 ℃ a -80 ℃ ma ka loaʻa ʻana. Manaʻo e hoʻokaʻawale i ka protein i nā mea liʻiliʻi no ka mālama maikaʻi ʻana. |
inoa mea kūʻai | Cat.ʻAʻole | Klone ID |
s100 β | AB0061-1 | 5H2-3 |
AB0061-2 | 22G7-5 | |
AB0061-3 | 21A6-1 |
'Ōlelo Aʻo: Hiki i ka Bioantibody ke hoʻololi i ka nui o kāu pono.
1. Ostendorp T , Leclerc E , Galichet A , et al.Nā ʻike hoʻolālā a me ka hana i ka hoʻoulu ʻana o RAGE e multimeric S100B[J].Ka EMBO Journal, 2007, 26(16):3868-3878.
2. R, D, Rothoerl, et al.Nā pae kiʻekiʻe o ka serum S100B no nā poʻe maʻi ʻeha me ka ʻeha ʻole o ke poʻo.[J].Neurosurgery, 2001.