Anti-kanaka SHBG Antibody, Mouse Monoclonal

ʻIke Nui
ʻO ka sex hormone binding globulin (SHBG) he glycoprotein ma kahi o 80-100 kDa;He kiʻekiʻe kona pilina no 17 beta-hydroxysteroid hormones e like me ka testosterone a me ka estradiol.SHBG
Hoʻoponopono ʻia ka neʻe ʻana i ka plasma e, ma waena o nā mea ʻē aʻe, ke kaulike androgen/estrogen, nā hormones thyroid, insulin a me nā mea meaʻai.ʻO ia ka protein transport nui loa no nā estrogens a me nā androgens i ke koko peripheral.ʻO ka ʻike ʻana o SHBG kahi kumu nui e hoʻoponopono ai i kā lākou māhele ʻana ma waena o nā mokuʻāina paʻa i ka protein a me ka manuahi.ʻO ka nui o ka plasma SHBG
pili i nā maʻi like ʻole, loaʻa nā waiwai kiʻekiʻe i ka hyperthyroidism, hypogonadism, androgen insensitivity a me ka cirrhosis hepatic i nā kāne.Loaʻa nā haʻahaʻa haʻahaʻa i ka myxoedema, hyperprolactinaemia a me nā syndromes o ka hana androgen nui.He mea pono ke ana o SHBG i ka loiloi ana i na ma'i palupalu o ka metabolism androgen a hiki i ka ike ana i kela mau wahine me ka hirsutism i oi aku ka pane ana i ka estrogen therapy.