Anti-kanaka GDF15 Antibody, Mouse Monoclonal
Nā kikoʻī huahana
ʻIke Nui
Growth-differentiation factor 15 (GDF15), i ʻike ʻia ʻo MIC-1, he lālā huna ia o ka transforming growth factor (TGF) -β superfamily, ma ke ʻano he novel antihypertrophic regulatory factor i loko o ka puʻuwai.ʻAʻole hōʻike ʻia ʻo GDF-15 / GDF15 i loko o ka puʻuwai makua maʻamau akā ua hoʻoulu ʻia i ka pane ʻana i nā kūlana e hāpai i ka hypertrophy a me ka cardiomyopathy dilated a ua hōʻike nui ʻia i ka ate.He kuleana ko GDF-15 / GDF15 i ka hoʻoponopono ʻana i nā ala inflammatory a apoptotic i nā ʻiʻo ʻeha a i ka wā o nā kaʻina maʻi.Hoʻopili ʻia ʻo GDF-15 / GDF15 e like me nā molekole precursor i hana ʻia ma kahi kahua cleavage dibasic e hoʻokuʻu i nā kikowaena C-terminal i loaʻa kahi ʻano kumu o 7 mau cysteine i mālama ʻia i loko o ka protein makua.ʻO ka overexpression GDF-15 / GDF15 e puka mai ana mai kahi ʻāpana erythroid i hoʻonui ʻia e hāʻawi i ka hao nui i nā maʻi thalassemia ma ke kāohi ʻana i ka ʻōlelo hepcidin.
Waiwai
| Manaʻo Pair | CLIA (Hopu-Hopu): 23F1-5 ~ 6C1-9 23F1-5 ~ 3A2-1 |
| Maemae | >95%, hoʻoholo ʻia e SDS-PAGE |
| ʻO ka hoʻopololei ʻana | PBS, pH7.4. |
| Waihona | E mālama iā ia ma lalo o nā kūlana sterile ma -20 ℃ a -80 ℃ ma ka loaʻa ʻana. Manaʻo e hoʻokaʻawale i ka protein i nā mea liʻiliʻi no ka mālama maikaʻi ʻana. |
Hoʻohālikelike hoʻokūkū
ʻIke Kauoha
| inoa mea kūʻai | Cat.ʻAʻole | Klone ID |
| GDF-15 | AB0038-1 | 3A2-1 |
| AB0038-2 | 23F1-5 | |
| AB0038-3 | 6C1-9 | |
| AB0038-4 | 4D5-8 |
'Ōlelo Aʻo: Hiki i ka Bioantibody ke hoʻololi i ka nui o kāu pono.
Kuhikuhi
1.Wollert KC, Kempf T, Peter T, et al.ʻO ka Prognostic Value of Growth-Differentiation Factor-15 i nā maʻi me Non-ST-Elevation Acute Coronary Syndrome [J].Kaapuni, 2007, 115(8):962-971.
2. Kempf T , Haehling SV , Peter T , et al.Prognostic pono o ka ulu 'okoʻa kumu-15 i loko o nā maʻi me ka maʻi puʻuwai hāʻule.[J].Nūpepa o ka American College of Cardiology, 2007, 50(11):1054-1060.
